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Theses/Dissertations from 2024

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Unearthing aggregation-induced emission active compounds in Alpinia galanga for breast cancer detection, Ma. Feliza B. Adorna, Hazel Mae L. Pacheo, and Victor Windsor A. Remulla

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Effect of zinc (II)-manganese (II)-cobalt (II) trace metal ion mixture on the growth of wild-type Lacticaseibacillus casei under nutrient-sufficient conditions, Jennica Karryne T. Albay, Marianne Joy J. Plantinos, and Angel Hanz Gabrielle I. Vales

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Isolation, characterization, and profiling of lactic acid-producing bacteria from homemade and selected Philippine fermented foods, Jan Beatrice A. Balungaya, Angel Kate P. Borja, and Rie Ochi

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Unlocking aggregation-induced emission potential in selected medicinal plants; towards the development of a point-of-care and rapid tuberculosis detection, Pauline Anne V. Barraquiel, Abdon Nathaniel N. Carullo, and Wyeth Alain S. Ebue

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Assessment of the antimicrobial activity of crude methanolic extract from Brassica oleracea L. var. acephala (curly kale) leaves against Pseudomonas aeruginosa, Joseph Patrick C. Bucao, Richard E. Delos Santos, and Michaela C. Martin

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Extraction and antimicrobial evaluation of oil from Homalomena philippinensis rhizome against Methicillin-resistant Staphylococcus aureus (MRSA), Gabrielle N. Claudio, Martha Stephanie A. Patricio, and Kerby S. Velasco

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Artificial intelligence (AI)-based protein structure prediction and linear peptide epitope identification in NanH, NanI, and NanJ for Clostridium perfringens vaccine applications, Eseankier Ritcher O. Cuevas, Leanna Angela D. Gaffud, and Rizalyn D. Leccio

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In vitro a-glucosidase inhibitory activity and phytochemical screening of Canarium ovatum pulp fractions, Anna Vheatrice E. De Villa and Zia Meidree C. Songcheng

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Molecular docking of SS aptamers to the cytosolic loops of steroid 5 a-reductase 2 (s5αr-2): towards the treatment of benign prostatic hyperplasia (BPH) and androgenic alopecia (AGA), Hiroyoshi M. Ohama and Melrinn Jeshua S. Rodis

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Design of ssDNA aptamer for the early diagnosis of prostate cancer via interaction with glutamate carboxypeptidase II, Rochella Mae T. Ramos, Bea Bianca N. Torres, and Princess Roseanne L. Zaide

Theses/Dissertations from 2023

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Docking studies of colored rice anthocyanins and related metabolites as potential inhibitors of colon cancer-related proteins, John Dhryll M. Abrazado and Joanna Kierstine N. Billote

In silico analyses of Cj0983- and Cj0090-derived epitopes for Campylobacter jejuni vaccine applications, Bennies T. Agnazata, Jamai Pruline D. Sale, and Monique M. Oro

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Molecular docking study of lignans as potential inhibitors of aromatase enzyme in breast cancer cells, Stefan R. Alcantara, Lea Neleen J. Camama, and Bernadine Anne R. Ebarola

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Chitosan-based bioplastic 3D filament from Talaba (Magallana bilineata) shells through heat extrusion process as a sustainable alternative to conventional filament: preparation, characterization, and FDM 3D printing, Reana Gail Q. Bargo, Janina Leigh N. Nemis, and Wilner D. Siarot

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In vitro analysis of carica papaya linn f1 hybrid leaf extracts as a potential aldh inhibitor in saccharomyces cerevisiae cells, Arrianne Mae D. Cajeric, Paul Francis N. Dela Cruz, and Yna Kirsten M. Mallo

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Computer-aided design of cotransin analogs as sec61 inhibitors for autoimmune disease, Nicole P. Canlas, Tiffany Anne E. Kwong, and Rizel Marie S.M. Ting

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In silico design of apratoxin s4 derivatives as potential ace2 down-modulators for Covid-19 treatment, Eliyah Claris C. Caringal, Gabrielle Denise H. Austria, and Christelle Atete

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Isolation of pediococcus acidilactici from selected Filipino foods and examination of its effect as cholesterol regulator, Allan Anthony G. Daypuyart II, Azzelle Mae L. Pecina, and Edriel John P. Estelloso

In silico analysis of quercetin derivatives as potential xanthine oxidase inhibitors in hyperuricemia-related conditions, Ferlyn Joyce M. De Jesus, Kurt Daniel L. Sunga, and Mikaela Gwyneth T. Valdez

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Assessment of mysterious fungi colonization in a climate-controlled national repository collections environment, Katherine Anne V. De Leon, Alyssa Gayle G. Garcia, Ian Istvan A. Infante, and Trisha Nicole Ann A. Manzano

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In silico analysis of selected repurposed drugs as potential inhibitor of ns5 protein of dengue virus serotype 2 (denv-2), Christian Angelo V. Kong, Angelica Jane S. Tabing, and Abigail Cristine L. Velasco

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Docking studies and design of Cyclotriazadisulfonamide (CADA) analogs as sec61 channel inhibitors for HIV treatment, Jay Gabriel B. Larga and Wrynan T. Munabirul

In silico analysis of allicin and its guanidinium-based derivatives as a potential antagonist of neuropeptide y receptor in Aedes aegypti, Nathan Daniel A. Ongkeko

Theses/Dissertations from 2022

Docking studies of the secondary metabolites of mimosa pudica as potential inhibitors of monoamine oxidase a for alleviating depression, Allysa Mae R. Abusmas, Christian Derik L. Aquino, and Victor Winsdor A. Remulla

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Design and docking studies of aristolactam derivatives as chorismate synthase inhibitors of mycobacterium tuberculosis, Ma. Patricia Eunice T. Ancheta, Heineken M. Frani, and Rannilo D. Rocas Jr.

Design and docking study of mangostin derivatives as potential asparagine endopeptidase inhibitors for parkinson’s disease, Athena Eunice C. Bandoy, Kheizz Alwen M. Bendo, and Franchesca Layne L. De Grano

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Molecular docking studies of anti-inflammatory Saponins as potential inhibitors of Rorγt against Psoriasis, Karen Franz A. Caoagdan, Nadine Julia A. Mamaril, and John Cedric P. Mojica

In silico studies of Coriandrum sativum components as δ-secretase inhibitors for Alzheimer’s disease treatment, Alyssa Doren R. Carig, Maria Isabela V. Castillo, and Kloei Zeneofe C. Ramos

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In silico analysis of selected flavonoids and phenolic acids of origanum vulgare (oregano) as an inhibitor against nana enzyme of streptococcus pneumoniae, Patrisha Beatrice A. Dela Cruz, Sweet Kaye C. Polintang, and Alexander James S. Reinoso

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In silico biding analysis of Sars-cov-2 main protease with selected secondary metabolites of lentinula edodes, Angelica D. De Matta, Lorraine Gabrielle M. Fernandez, and Marie Anetonnette F. Flores

In silico analysis of Alliin derivatives as potential antiviral compounds against COVID-19, Krista Mi'Cole P. Goitia

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Design and in silico analysis of pf-07321332 derivatives as potential inhibitors of sars-cov-2 mpro, Lian Ross P. Greenwood, Audrey Gwyneth M. Lingatong, and Sophia Latrize Mari R. Rocha

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Pharmacological analysis of C-glycosyl flavonoids and molecular docking to delta, kappa, and mu opioid receptors to determine possible antinociceptive property, Sofia-Gail G. Hernandez, Rianne Sheryn G. Jovellana, and Hiroko Paqueo

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Molecular docking studies of selected compounds from Coprinopsis lagopus as potential UBC13 inhibitors for breast cancer treatment, Paolo C. Miral, Lance Raven A. Pisco, and Clarence Angelie M. Rubio

Theses/Dissertations from 2021

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In silico potential antibacterial and antiviral properties of the major allergen-derived bioactive peptides from Arachis hypogaea seeds, Wren Leanro I. Aguila, Roseanne Mae P. Ortilano, and Alfonso Beato T. Revilla

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Amino acid modification in papain at key active sites for possible activity optimization against cystatin D inhibitor, Cyrille A. Amper, Mhexianne H. Pollante, and Seth Yves Villanueva

Molecular docking studies of secondary metabolites from Abelmoschus esculentus L. as potential inhibitors of InhA in multidrug-resistant mycobacterium tuberculosis, Joan Camille M. Aquino, Aileen Mae D. Arban, and Sylvie K. Niyitanga

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In silico evaluation of secondary metabolites of sonchus oleraceus linn. as potential inhibitors of SARS-COV-2 main protease, Patiricia Anne L. Aquisap, Crystal Yara D. Fernandez, and Bianca Louize A. Llavore

In Silico prediction and validation of unique antigenic epitopes from Human Pegivirus (HPgV) for possible immunodiagnostic applications, Nick Austin A. Bayot, Nier Byron B. Reyes, and Maria Athena G. Villarroel

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Molecular docking analysis of selected secondary metabolites from green tea (camellia sinensis) against influenza A (H1N1) neuraminidase, Noreen Claire G. Bunyi, Shaina Patrice R. Opeña, and Roseanne Mae P. Taniajura

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In silico docking analysis of selected phytochemicals with dipeptidyl peptidase (DPP)-IV, Christensen P. Calibo, Jewel Denisse T. Fontanilla, and Julia Beatriz I. Bartolome

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Molecular docking study of selected secondary metabolites from marine macroalgae as potential angiotensin-converting enzyme inhibitor, Gabriel Sebastian D. Calingin, Adam G. Malijan, Dan O. Ribo, and Erdsan Rene O. Suero II

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Possible inhibitory effects of carbohydrates and steroids found in selected Philippine plants on bile salt hydrolase, Reijean T. Caraig, Jason Lawrence M. Ferranco, and Benedicto G. Pasadilla Jr.

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In silico evaluation of tetracera scandens secondary metabolites as potential HIV reverse transcriptase inhibitors, Moira Kirstel Chand, Paulo Emilio Vincenzo C. Mangubat, and Eia Guadalupe L. Timbreza

In silico determination, peptide engineering demonstration, and preliminary docking studies of potential antimicrobial peptides from cocosin-1 againts methcillin-resistant Staphylococcus aureus Muramyl E (MurE) Ligase, Driyah Nicole E. Dario, Kuven A. Malig-on, and Anna Fatima M. Perea

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Molecular docking studies of selected secondary metabolites from Laportea interrupta as potential UBC13 inhibitory for human breast cancer therapy, Arcely P. Echanique, Diane Elreen Sol L. Set, and Ranali G. Tangog

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Docking studies of selected secondary metabolites of vigna radiata sprouts as asparagine endopeptidase inhibitors for Alzheimer’s disease, Katrina Lyn S. Flores, Aryanna Lian A. Lim, and Marie Louise H. Ondis

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Molecular docking studies of secondary metabolites from canarium ovatum as potential α-amylase and α-glucosidase inhibitor, Ramon Baltazar Herrera, Albert Andollini Peña, and Tabanao Matthew Ira

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Possible inhibitory effects of prebiotics and secondary metabolites from selected indigenous plants from Rwanda and Solomon islands to the beta-galactosidase of bifidobacterium bifidum, Ngabo Herve and Rex Q. Vilaka

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In silico studies of Coleus aromaticus compounds as SARS-CoV-2 RNA-directed RNA polymerase (RdRp) inhibitor, Ma. Kyla C. Naingue, Maphel Angelica C. Pasao, and Kate P. Reyes

Theses/Dissertations from 2020

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Isolation and quantification of crude protein extract form the pulp and aril of the momordica cochinchinensis fruit, Jan Alexis Bernadette Calderon, Rahul Paul, and Pratik Devendra Sati

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The possible role of selected antidepressant metabolites in antitumor immunity: a molecular docking study of granzyme B, John Raphiel C. Macatangay

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Isolation and quantification of total proteins from the mesocarp of cerbera manghas Linn. fruit and evaluation of its in silico hemolytic activity using thevetia peruviana as plant model, Quennie Marie P. Orido and Yoshiki M. Ohama

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In silico design of five pyridomycin derivatives as potential inhibitors of InhA and multidrug-resistant M. tuberculosis, Kolosu Sakiusa, Joshua Verrick C. Martin, and Edvard Ndahigwa Ntambara

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In silico diversity analysis of the 16S rRNA gene of the bacteria isolated from mobile phones and development of SNP primers for predominant bacterial species, Blessey Shaji Tomas and Vanesse Senga

Theses/Dissertations from 2019

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Green synthesis of iron oxide nanoparticles using Ipomoea aquatica leaves extract and their antibacterial activity, Muhammed Suhail Ashraf, Yashkumar M. Kandoi, and Ingabire Karangwa Ines Lorenzo

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Angiosuppressive effect of the ethanolic extracts of Calocybe indica and Pleurotus ostreatus in combination with paclitaxel on duck chorioallantoic membrane, Monil M. Baghadia

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Identification of Vibrio cholerae and coliform analysis of Labac River (Naic Station) and its physicochemical assessment, Patricia Denise S. Bautista and Sheila May T. Ilano

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Comparison of antioxidant activities of the extracts from Hibabao (Broussonetia luzonica) flowers and leaves, Serge K. Bizaba, Elmer B. Dominguez, and Oluwajomiloju K. Kehinde

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In vivo antidepressant-like effect of the ethanolic extract of Cynometra ramiflora L. leaves in ICR mice, Mikaela Nicole M. Bracamonte, Pamela Kim Ineza Karega, and Yuting Wang

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Diuretic effect of ethanolic extract of Lansium domesticum fruit peel on Mus musculus domesticus, Jessica Therese O. Cabildo and Reinelle R. Pesante

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In vivo antidepressant-like effect of the ethanolic extract of Muntingia calabura leaves in ICR mice, Sharai Yakee L. Chen, Micah Beatrice N. Manalo, and Kaye Gwyneth D. Naldoza

Cellulase and pectinase assisted extraction of total carotenoids from lemon (Citrus limo) peels, Reign Matteus N. Gocoyo and John Paul G. Natividad

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Isolation and partial characterization of the combined antibacterial proteins from leaves and stem of Mimosa pudica Linn, Apurva Kaushik and Salman Ahammed

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Biosynthesis, characterization, and antibacterial activity of zinc oxide nanoparticles using Croton tiglium (Croton) leaf extract, Nicole Aurichael B. Maribbay, Shashi Shailesh Kumar, and Xania O. Ramos

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In vitro screening of antioxidant activity and α-Glucosidase inhibitory activity of selected Philippine Ficus Species, Ruth M. Njeru Wariba, Katrina Joyce V. Trajano, and Eunice Anne Q. Zoleta

Green synthesis of silver nanoparticles from Annona muricata leaves extract against Staphylococcus aureus and escherichia coli, Ma. Ericha Janelle E. Parado

Theses/Dissertations from 2018

In vivo antipyretic and analgesic effects of the ethanolic extract of Bauhinia malabarica leaves in ICR albino mice, Aaranda G. Abello, Sheena Ria O. Cadavedo, and Angelaid M. Vizcarra

In vivo antidepressant-like effect of the ethanolic extract of Lagerstroemia speciosa leaves in ICR albino mice, Kris Anica V. Ablir, Kezia Raynina E. Agoncillo, and Zamil D. Magdamit

In vitro screening of antibacterial activity of selected Schefflera species, Jema Creightania L. Agda, Earvin Ray V. Asinas, and Vienne Audrey C. Rada

Comparative profiling of some grain quality traits of milled rice from SM Hypermarket and wet market in Kadiwa, Dasmariñas City, Cavite, Hanz Cez R. Albino and Kassandra Cay P. Camanag

Antidiarrheal effects of a commercially available probiotic drink on ICR albino mice (Mus musculus var. albino), Raniel John L. Alcantara, Ma. Irel Geodess L. Rodegerio, and Justine Clarizze P. Umayam

Adsorption isotherms of modified zeolites on the removal of bromophenol blue on aqueous solutions, Alyssa Denice A. Alindao, Micah Kate L. Dela Cruz, and Raphael Tristan Roy A. Palisoc

Biosynthesis of silver nanoparticles using Premna odorata (Alagaw) and Saccharum spontaneum (Talahib) leaves and their larvicidal activity against aedes aegypti, Joe Marie R. Amores, Charisse F. Ancheta, and Alyson D. Tomelden

In vitro screening of antimicrobial activity of selected Philippine ficus species, Nihika Therisse R. Anteja, Rouisa Vianna B. Lopez, and Alpha Divina S. Nolasco

Total phenolic and flavonoid content of ethanol extracts from selected Philippine endemic plants, Trisha Mae D. Arcena, Shen Alyssa O. Awid, and Jhyl Dimple E. Leyso

In vivo antidepressant-like effect of the ethanolic extract of Alternanthera bettzickiana whole plant in ICR albino mice, Keziah Jeremy P. Astilla, Peter Paul G. Glemao, and John Reynald V. Manalo

Phytochemical analysis and determination of the in Ovo cytotoxic effects of Phyllanthus niruri Linn. leaf extracts against Salmonella enteritidis, John Jayvee R. Balboa, Satria Nicole C. Granados, and Anita L. Merin

Isolation, purification and partial characterization of Azadirachta indica leaf extract, Rohit K. Ballagan, Tim Martin A. Sibayan, and Raulan G. Tangog

Antimicrobial properties of bioluminescent bacteria from Decapterus macarellus, Ma. Eluisa R. Bangloy, Gail Mariel M. Carandang, and Hazellene M. Javal

In vivo antidepressant-like effects of the ethanolic extract of Malvastrum coromandelianum (L.) Garcke leaves in ICR albino mice, Anne Gabrielle M. Bautista, Raphael Adrian A. Cruz, and Andrea M. Manalo

Isolation, purification and partial characterization of Fagraea racemosa leaf extracts, Ma. Keith Lalaine P. Bruno, Camilla Gabrielle C. Claveria, and Yuriann Angelica Pempengco

Isolation and partial characterization of proteins from the seeds of Lantana camara L. exhibiting antibacterial activity, Yvonne R. Caguimbal, Kiarra Ysabel R. Gamat, and Luise U. Sablaon

Isolation, purification and partial characterization of Tabernaemontana pandacaqui leaf extracts, Kathleen Mhae P. Castillo, Mari Katerin Michel R. Gacoba, and Xilin Wang

Development and validation of a digital photometric method for milled rice apparent amylose content determination using a smartphone camera, Gabrielle A. Castrillo and Gabriel Angelo V. Viola

In vitro screening of antimicrobial activities of selected Philippine Clerodendrum and Rotheca species, Roxandra Grace V. Ceburon, Clarisse Kaye M. Dacuray, and Maria Kristel Ciarina M. Macalintal

Isolation, purification and partial characterization of Areca ipot leaf extracts, Gourev K. Chawla, Norberta C. Dela Cruz III, and Barbra B. Odhiambo

Antioxidant activity of soluble proteins and their peptic hydrolysates from commercially available corn flakes, Joshua V. Dalmacio and Cristine Joyce M. Pestano

Selected physical and chemical attributes of market non-waxy milled rice from selected supermarkets in Muntinlupa City, Nyla Jenyn V. David and Leonard T. Famy IIII

Antimicrobial activity and total phenolic and flavonoid contents of Medinilla magnifica Linl. leaf extracts, Mariel Joy V. Delgado, Darlah Marcela S. Leonardo, and Eunice N. Mabansag

Anti-angiogenic activity of selected roasted coffee bean extracts using chick chorioallantoic membrane assay, Najie Anne D. Diamse, Judelle Mari E. Hernando, and Nova Suzette Tolentino

Antiangiogenic properties of Averrhoa bilimbi Linn, and Syzygium polycephaloides using chick chorioallantoic membrane assay, Eddha Divine C. Divinagracia, Mojica M. Manhan, and Jeanne Pamela G. Tayag

Yield and antioxidant capacity of total carotenoids from lemon peels extracted via enzyme-assisted extraction using microbial cellulase and xylanase, Audrey Dana F. Domingo and Vyanka Teia Leeniza M. Gonzales

Isolation and partial characterization of antibacterial proteins from Eleusine indica Linn. Leaves, Jazel Mariz S. Dragon, Shuna Jangao Kaga, and Julie Ann Arbo Trinidad

In vitro screening of antibacterial activity of selected merremia species, Trina Ysabel N. Espiritu, Jezreel Kate, and Anfiona Jairah T. Sison

Isolation, purification and partial characterization of Cynometra ramiflora leaf extracts, Karl Jamiel B, Funtaneres; Daniella Erica R. Kasilag; and John Paul M. Ramos

In vitro alpha-glucosidase inhibitory effects of various plants from cucurbitaceae family, Jazmine Shayne A. Gabat, Christianne Sophiamarie S. Perez, and Jeanne Kyla A. Ricalde

Isolation, purification and partial characterization of Clausena sanki (Perr.) Molino leaf extracts, Aubrey Anne C. Garde, Edjune M. Lingan, and Quennie B. Tiquis

Angiogenic analysis of Jasminum sambac Linn. leaf extract using chorioallantoic membrane assay in duck egg, Rona Elaine R. Garduque, Shane Cathlene E. Noma, and Beverly J. Sabado

Synthesis and characterization of activated carbon-calcium carbonate nanomaterials for air contaminants filtration, Jonathan Blake A. Gatchalian, Marielle Karol Bernise M. Gonzales, and Hera Princess C. Kikuchi