The relationship between hematologic inflammatory markers and clinical outcomes among COVID-19 confirmed patients in a tertiary hospital in Dasmariñas City, Cavite, Philippines : a cross-sectional study

Publication Date

2022

Document Type

Article

Abstract

This study is a retrospective, single-center, analytical cross-sectional design conducted on 182 patients with COVID-19 infection who were admitted to DLSUMC from March 2020 to March 2021. Peripheral blood count were taken to determine the NLR, SII, SIRI, and AISI. Results of the hematologic markers and its association with COVID-19 severity were analyzed using multivariate regression analysis. Among the 182 patients diagnosed with COVID-19 infection, 63 (34.6%) were categorized into the moderate group and 55 (30.2%) intro the severe group upon admission. The mean NLR, SII, SIRI and AISI directly increases as the severity worsens. After multiple regression analysis, NLR and SII were independently associated with ICU admission, with SII performing better than NLR (AUC 0.745 vs 0.694), while SIR and AISI were more likely to predict development of ARDS than the other markers, with SIRI having a higher diagnostic accuracy (AUC 0.718 vs 0.689).

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