An unexpected twist : a case of coexistence of hereditary spherocytosis and hemoglobin e thalassemia
Publication Date
2013
Document Type
Research
Abstract
A case of a 22 year old Filipino female who presented with abdominal pain. Work up revealed cholethiases and coexistence of HS and Hgb E thalassemia. Diagnosis for HS was based on: 1) clinical findings of splenogmegaly, jaundice, anemia and cholelithiases, 2) having a sibling diagnosed with HS, 3) peripheral blood smear revealing presence of spherocytes, and 4) increased osmotic fragility of the erythrocytes both with and without incubation. Diagnosis for Hgb E thalassemia was determined by 1) alkaline electrophoresis findings most compatible with hemoglobin E trait and 2) HPLC chromatography tracing revealing beta thalessemia, E-interacting with HbA2 levels at 32.3%.
APA Citation
Tanchanco, Camille Adriadne C. and Concepcion, Maria Luisa, "An unexpected twist : a case of coexistence of hereditary spherocytosis and hemoglobin e thalassemia" (2013). Resident Research. 69.
https://greenprints.dlshsi.edu.ph/resident-research/69