Thyroid function profile among Down Syndrome pediatric patients in the endocrinology clinic of De La Salle University Medical Center and St. Paul Hospital, Cavite : a 10 year review
Publication Date
2019
Document Type
Research
Abstract
A retrospective cross-sectional study. A total of 43 cases of Down Syndrome were seen. No gender predominance noted. The most common maternal age and paternal age at childbirth is 35-39 years old and 40-44 years old respectively. All Down Syndrome with karyotyping were nondisjunction type. A family history of thyroid disorder had no correlation with Down syndrome with thyroid disorder. Cardiac anomalies were the most common co-morbidities. Initial thyroid function tests were mostly done at 6 moth of age and showed Hyperthyrotropinemia, as most common result. Around 20 patients were diagnosed with thyroid disorders with a prevalence rate of 46.5%, mostly diagnosed at the age of 1-2 years old and developed acquired hypothyroidism. Outcome of thyroid status on follow up were variable.
APA Citation
De Leon, Angela Marie L., "Thyroid function profile among Down Syndrome pediatric patients in the endocrinology clinic of De La Salle University Medical Center and St. Paul Hospital, Cavite : a 10 year review" (2019). Resident Research. 299.
https://greenprints.dlshsi.edu.ph/resident-research/299