Baseline assessment of renal function by random serum creatinine as a risk stratification tool for prediction of occurence of superimposed preeclampsia in pregnant patients with chronic hypertension

Publication Date

2019

Document Type

Research

Abstract

A retrospective cohort study from 2014-2018 was done. Eighty sex women wit singleton pregnancy, diagnosed with chronic hypertension at the charity outpatient department of De La Salle University Medical Center were included. Statistical analyses were performed using SPSS 3.0. The optimal mathematical cut-off for baseline serum creatinine was determined using area under the curve method and p-values < 0.05 were considered significant. Results showed that baseline serum creatinine cut-off valued at < 20 weeks AOG is at >0.71 mg/dL with a sensitivity of 69.2% and specificity of 75% to predict the occurrence of superimposed preeclampsia, whereas, baseline serum creatinine cut-off value at >28 weeks age of gestation is at >=0.625 mg/dL, with a sensitivity of 62.5 and specificity of 71.4.

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