Validation of hematologic scoring system in early diagnosis of neonatal sepsis in the neonatal intensive care unit of a tertiary hospital in Dasmarina

Authors

Yuly

Publication Date

2014

Document Type

Research

Abstract

This study is to determine the validity of the hematologic scoring system for early diagnosis of neonatal sepsis in a local setting. All neonates born and admitted in the neonatal intensive care unit of a tertiary hospital in Dasmarinas, Cavite from 2008 to 2012 who are clinically septic and with blood culture determination. all of the hematologic scoring system parameters were significantly associated with culture outcome (p< 0.001). Highest sensitivities among parameters noted in Total PMN count (100%) and I:T PMN ratio (96%). The highest specificities were immature PMN count (100%) and I:M PMN ratio (100%). the validity of the hematologic scoring system with cutoff at less than equal 3 points, described as follows : sensitivity was 96.36% and specificity is 100%. The overall accuracy was 98.18%. All of patients with total scores of less than equal 3 points can predict positive culture finding. The negative likelihood ratio was 0.0364.

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