Date of Completion

2024

Document Type

Research Project

Degree Name

Grade 12

Keywords

Allicin, Staphylococcus Aureus, Antimicrobial Activity, Disinfectant, Efficacy

Abstract

Garlic (Allium Sativum L.) is esteemed for its potent antimicrobial properties, owing to its abundance in organosulfur compounds like allicin, ajones, and allyl sulfides, which have been extensively researched for their efficacy against various bacterial and fungal pathogens, notably Escherichia coli, Staphylococcus aureus, and Propionibacterium acnes. Its multifaceted medicinal benefits, spanning from antioxidant and anti-cancer properties to immune-boosting effects, have spurred interest in its potential for combating diseases such as obesity, cardiovascular ailments, and even COVID-19. Employing a Single Subject Experimental Design. Aqueous Garlic Extract, prepared according to established protocols, underwent evaluation as a disinfectant against common toilet and bathroom pathogens, employing A-B-A Designs for comparison against baseline measures post-treatment comparison. Results showcased the significant antimicrobial activity of Garlic (Allium Sativum L.), credited to its organosulfur compounds, rendering it a promising disinfectant against bacteria. The study aimed to develop an eco-friendly disinfectant utilizing Allium Sativum L. aqueous extract, assessing its efficacy against common pathogens. Various extract concentrations (EC50, EC100) were tested, with comparisons drawn against both natural-based and commerciallyproduced disinfectants. Statistical analyses, including One-Way ANOVA and Tukey Post Hoc Analysis, revealed noteworthy differences between treatments, facilitating the identification of effective and environmentally friendly disinfection solutions. However, the researchers claim that the efficacy replacement of concentrations couldn’t replace the efficacy of Lysol®, as the researchers didn’t fall to the acceptable colony count factor

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