Pericardial effusion as an initial manifestation of systemic sclerosis in a patient with stable hashimoto's thyroiditis
Publication Date
2019
Document Type
Research
Abstract
Systemic sclerosis is an autoimmune disease that manifests with puffiness of the face and extremities, followed by hyperpigmentation, and then eventual symmetrical skin thickening due overproduction and accumulation of collagen. It is a rare disease with a high female predominance. Cardiac involvement only occurs in 9-12% of cases but is unusual to be one of the initial manifestations. This is a case of a 39-year old female, with known hypothyroidism in euthyroid state for 4 years, presented with non-tender bipedal pitting edema and an incidental finding of pericardial effusion with beginning tamponade on 2-dimensional echocardiogram. Multiple consults and various therapeutic interventions were done with no resolution of symptoms. Eventually, patient was referred to a rheumatologist wherein skin biopsy of the leg revealed scleroderma. Resolution of edema was noted upon introduction of disease modifying antirheumatic drug. The presence of pericardial effusion can be confounding in this case because of concomitant hypothyroidism but its occurrence is unlikely because patient is in euthyroid state at the time of diagnosis.
APA Citation
Lozano, Noryn Tweela P.; Fernandez, Eizelle M.; and Pagsisihan, Daveric A., "Pericardial effusion as an initial manifestation of systemic sclerosis in a patient with stable hashimoto's thyroiditis" (2019). Resident Research. 90.
https://greenprints.dlshsi.edu.ph/resident-research/90