Risk factors associated with in-hospital complication post gastrointestinal, pancreatic, hepatic cancer surgery : a case control study (RAPHa study)

Publication Date

2000

Document Type

Research

Abstract

All adult patients 18 years old and above who underwent gastrointestinal, pancreatic and hepatic cancer from January 1, 2010 to July 30, 2014 were included. Variables with p value < 0.20 in the univariate analysis were included in the multivariate analysis. Logistic regression techniques were used for model development in order to obtain a specific score and an equation. Independent prognosis factors emerging from these logistic regression models were used to develop the scoring system to determine the best cut-off score in predicting in-hospitality morbidity. Out off 142 patients who developed complications post-operatively, univariate analysis revealed that age (p=.001), abnormal hemoglobin (p=0.0592), WBC (p=0.001), serum creatinine (p=0.007), serum sodium (p=0.018), serum potassium (p=0.0013) and serum albumin (p< 0.0001) were more prone to develop complications post-operatively. On multivariate analysis, results showed that only age ≥ 75 years (p value = 0.002), low serum albumin (p value = 0.00), abnormal ECG findings (p value = 0.036) and emergency surgery (p value = 0.000) were only significant associated with morbidity. The equation was formulated using the regression analysis and best cut-off score was determined to be at 1.4.

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