Monotherapy versus dual antiplatelet therapy on posterior circulation ischemic stroke: a prospective study on its effect on early neurological deterioration and early recurrence of ischemic stroke

Publication Date

2015

Document Type

Research

Abstract

A prospective cohort study on patients admitted at De La Salle University Medical Center for posterior circulation ischemic stroke was conducted. The patients were classified according to treatment groups: monoantiplatelet and dual antiplatelet group. Patients were followed up for 90 days. Primary outcomes were early neurological deterioration (END) and early recurrent ischemic stroke (ERIS). Secondary outcomes were morbidity, bleeding and all-cause mortality. The study concluded that there is almost equal percentage of occurrence of END in mono and dual antiplatelet group. A trend in increased bleeding in dual antiplatelet group is seen as compared to monoantiplatelet group. However, this is an initial descriptive results of the study and additional subjects are needed in order to determine a statistical significance between the two groups.

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