Date of Completion

2024

Document Type

Research Project

Degree Name

Grade 12

Keywords

Flammulina filiformis, Staphylococcus aureus, antibacterial properties, zone of inhibition, susceptibility, extract.

Abstract

There are already a few types of mushrooms that have exhibited their antibacterial properties against certain bacteria, but these studies are limited to a certain scope only. This study aims to further examine the antibacterial properties of Flammulina filiformis against Staphylococcus aureus. The study utilized an experimental research design employing Kirby- Bauer disk diffusion method. The results revealed that the antibacterial properties of Flammulina filiformis extracts were evident against Staphylococcus aureus at various concentrations. Moreover, higher concentrations of the extract showed greater efficacy against Staphylococcus aureus. This indicates a significant variation in antibacterial properties among different concentrations of Flammulina filiformis based on the zone of inhibition. There was a significant difference in the zone of inhibition between the different concentrations of the extract and the Vancomycin. The study suggests that Flammulina filiformis extract demonstrated effective antibacterial activity as Staphylococcus aureus showed susceptibility to the varying concentrations exhibiting a considerable diameter of zone of inhibition. Since Flammulina filiformis has shown promising antibacterial effects, the Department of Health could start clinical trials to test how well Flammulina filiformis extract works in treating Staphylococcus aureus infections and other similar bacterial infections in humans.

First Advisor

Pancho E. Ercilla

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