Characterization of the swelling and antimicrobial properties of kamote (Ipomoea batatas) starch-based hydrogel wound dressing (HWD) infused with talahib (Saccharum spontaneum linn.) ethanolic plant extract against methicillin-resistant Staphylococcus aureus (MRSA) and Candida albicans

Date of Completion

2023

Document Type

Research Project

Degree Name

Grade 12

Keywords

Hydrogel Wound Dressing (HWD), Candida albicans, Staphylococcus aureus, Kamote, Talahib, Swelling Rate, Antifungal Properties, Antimicrobial Properties

Abstract

Due to their rising prevalence and cost, chronic wounds impose a significant economic burden on the healthcare system. Hydrogel Wound Dressings (HWDs) are utilized to facilitate chronic wound healing, but they are often expensive. Thus, this research aimed to produce a starch-based HWD that would serve as a cheaper and more accessible alternative without compromising its efficacy. In this study, two main experimental groups were involved with the swelling rate: kamote starch HWD (Group A), kamote starch HWD infused with talahib ethanolic plant extract (Group B). The samples were subjected to a swelling rate test, antibacterial test against Staphylococcus aureus, and antifungal assessment against Candida albicans. Upon the computation and assessment of the raw data for the swelling rate, Group A HWDs were characterized to be superabsorbent, with a mean exceeding 250%, while Group B exhibited a swelling rate of 239.90%, indicating absorbent properties. It was also

shown that there is a significant difference between the pre- and post- weights of the HWDs after SWF immersion for 24 hours, further

emphasizing their swelling capabilities. Yet, Groups A and B showed no significant difference in the means of swelling rate, indicating no adverse effects on the swelling rate despite the presence of talahib extract. On the other hand, the antimicrobial and antifungal properties yielded no results due to absence of inhibition. Overall, kamote-starch HWD demonstrated potential in terms of its swelling properties. However, further investigation is required to assess its effectiveness in terms of its antimicrobial and antifungal properties.

First Advisor

Pauline Cueno

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