Date of Completion

5-2019

Document Type

Thesis

Degree Name

Bachelor of Science in Pharmacy

Keywords

Plant Mucilage, Metformin, Phaseolus vulgaris, binder

Abstract

Using Sharma and Koul method, the yield of mucilage was found to be 12.52%. The granules were formulated by wet granulation method using the extracted mucilage as binder at 15%, 20%, 25% w/w concentrations. The study concluded that an increase in mucilage concentrage results in retardation of drug release. The dissolution and assay results did not pass the USP requirement for Metformin HCl extended release tablet due to possible excipient incompatibility and loss during manufacturing.

First Advisor

Leigh Don T. Villanueva, RPh

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