A systematic review of literatures of plants with angiogenic potential

Date of Completion

2021

Document Type

Thesis

Degree Name

Bachelor of Science in Nursing

Keywords

Plants, Angiogenic Potential

Abstract

The study utilized a systematic review of literature design. Research on genus Flemingia was obtained from reliable and accessible online resources such as Google Scholar, Pubmed, Elsevier Health and Sciences, Clinical key and Clinical Key Nursing, Science Direct, NCBI, Proquest, and CINAHL. The researchers utilized purposive sampling. Meta-synthesis and narrative synthesis were utilized to carefully review and avoid the repetition of data. Based on the findings of the study, F. Strobilifera, F. Macrophylla, and F. stricta can be utilized for their other pharmacologic effects such as treatment or management for fever, acidity, dysentery, diarrhea, hysteria, insomnia, pain, anxiety, and diabetes but no literature supports its angiogenic promoting activities. Plants under genus Flemingia such as F. philipinensis, F. macrophylla, and F. latifolia were observed to have phytochemicals such as auriculasin and flavonoids which inhibit vascular formation, cell proliferation and chemotactic migration. Other species under genus Flemingia showed anti-inflammatory activities on carrageenan-induced edema due to the presence of flavonoids, saponins, phenols, alkaloid, steroids. On the otehr hadn, F. stricta, F. philippinensis and F. wightiana contained anti-oxidtive activities which boost the immune system and protect cells from oxidative stress which may help in preventing some diseases such as cancer, diabetes and other cardiovascular disorders. Moreover, F. vestitia contained significant antimicrobial and antifungal effects due to its phytochemical components which cover organisms such as Eschericia coli, Bacillus subtilis, Shigella dysentriae, Aspergillus niger and fungi.

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