Date of Completion

2025

Document Type

Thesis

Degree Name

Bachelor of Science in Medical Laboratory Science

Keywords

BlaGES, ESBL, Escherichia coli, surveillance, treated water

Abstract

Extended-Spectrum Beta-Lactamase-Producing Escherichia coli (ESBL-producing E. coli) and its ability to survive in wastewater poses a great concern to the environment. This study shows the primary surveillance of ESBL-producing E. coli in a tertiary hospital’s water treatment plant. Multiple-tube fermentation technique was used in the determination of MPN while real-time polymerase chain reaction was utilized to confirm the presence of the blaGES gene in the isolated E. coli. Samples were collected in fifteen replicates for each month. The data gathered showed that all monthly samples showed an MPN of >8.0/100mL. All samples also demonstrated a negative result in RTPCR for the blaGES gene, signifying that no blaGES-positive ESBL-producing E. coli was observed during the three-month surveillance period.

First Advisor

Jennilyn Nicole G. Mendoza, RMT

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