Date of Completion

2024

Document Type

Thesis

Degree Name

Bachelor of Science in Medical Laboratory Science

Keywords

Antioxidant, Ethanol Leaf Extract

Abstract

Free radicals, highly reactive and unstable molecules, play pivotal roles in numerous biological and chemical processes, exhibiting a dual nature with both harmful and beneficial aspects. The understanding of antioxidants has evolved across natural and synthetic realms. Psidium guajava (Guava) and Musa x paradisiaca (Banana) have undergone extensive study for their antioxidant activity. This investigation explores the synergistic antioxidant effects of ethanolic leaf extracts from Psidium guajava and Musa x paradisiaca. Total Phenolic Contents (TPC) of the plant samples were quantified in gallic acid equivalents, % scavenging activity, and IC50 value in DPPH assay. Results reveal guava extracts with higher phenolic content at 21.13 mg/g compared to banana at 19.40 mg/g, indicating guava's significant antioxidant potential. IC50 values for banana, guava, and the combined solution appear slightly lower than guava alone, but higher than banana alone. While the mixture retains antioxidant activity, it may not match the effectiveness of guava alone, suggesting Psidium guajava as a more potent antioxidant when used independently, are 57.42 ug/mL, 36.53 ug/mL, and 45.96 ug/mL, respectively. Combined solution efficacy appears slightly lower than guava alone, but higher than banana alone. While the mixture retains antioxidant activity, it may not match the effectiveness of guava alone, suggesting Psidium guajava as a more potent antioxidant when used independently.

First Advisor

Jion P. Dimson

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