Factors associated with mortality among Acinetobacter baumanniii infected patients in a tertiary hospital in the Philippines

Publication Date

2020

Document Type

Research

Abstract

The study investigated 200 patients who developed A. baumannii infection during a 57-month period from January 1, 2016 to September 30, 2020. Of the 200 patients, 93(46%) died. Majority of infections were isolated from endotracheal aspirate, mostly resistant to penicillins, cephalosporins, aminoglycosides, quinolones, carbapenems, and co-trimoxazole. Major predictors of mortality were neurologic comorbidity [odds ratio (OR) of 2.21, 95% confidence interval (CI) of 1.10 - 4.44; p-value=0.019], hemodialysis (OR= 2.97, 95% CI= 1.16 - 7.58; p-value=0.042), mechanical ventilation (OR= 7.58, 95% CI= 3.95 - 14.49; p-value< 0.001) and central line placement (OR=5.21, 95% CI=2.01 - 13.51). Meanwhile, major surgery was found to be a protective prognostic factor of mortality (OR= 0.68, 95% CI= 0.36 - 1.29; p-value=0.012).

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