Analysis of adverse pregnancy outcomes using the glycemic cut-offs stated by the IADPSG, POGS and WHO diagnostic criteria for gestational diabetes mellitus in De La Salle University Medical Center (DLSUMC) from January 2012 - December 2015

Publication Date

2016

Document Type

Research

Abstract

The objectives of the study is to determine the association between adverse perinatal and neonatal outcomes with 75g OGTT levels according to cut-off values prescribed by the World Health Organization (WHO), Philippine Obstetrical and Gynecological Society (POGS), and the International Association of Diabetes in Pregnancy Study group (IASDPG) criteria to define a more appropriate cut-off for Filipinas. Retrospective cohort study of pregnancy deliveries in De La Salle University Medical Center (DLSUMC) from January 2012 to December 2015 was done. Subjects included were aged 18 and above who had a singleton pregnancy without other existing comorbidities, with a 75g OGTT result and complete medical record. Perinatal and neonatal outcomes were recorded and their association with the different glycemic cut-offs stated by the WHO, POGS and IADPSG were analyzed. Total of 195 subjects were included. Patients with an FBS≥126 mg/dL were more likely to have pre-eclampsia and preterm delivery, however, there is a significant number of GDM patients (22.3%) not diagnosed by this higher FBS cut-off. Maternal outcomes showed increased risk for preterm delivery with the 1-hour OGTT of ≥180 mg/dL and gestational hypertension with the 2-hour OGTT of ≥140 mg/dL.

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