Comparison of clove (Syzygium aromaticum) oil extract and commercially-available insect repellent against Aedes aegypti mosquito on rats

Date of Completion

2016

Document Type

Thesis

Degree Name

Clinical Pharmacology

Keywords

Syzygium, GataR transcription factor, Aedes aegypti, Rats, Insect Repellents

Abstract

This study aimed to determine the effectivity of a plant-based insect repellent, Syzgium aromaticum, as a natural repellent agent against Aedes aegypti mosquitoes. Extraction of the Syzygium aromaticum was done using steam distillation method. An experimental study was then devised using a glass cage divided into three parts with particular treatments-including water, clove extract, and a commercially available mosquito repellent, Off!. One Sprague Dawley rat applied with the corresponding treatment, and 50 female Aedes Aegypti mosquitoes were placed in each of the divisions of the glass cage. A total of three (3) trials, with one-day intervals, were done and the findings revealed that the commercially available mosquito repellent had the most effective repellent activity against Aedes aegypti mosquitoes as it produced the lowest average number of mosquitoes landing on the test area. This was followed by the clove extract, and the placebo group. Statistical analysis showed a significant difference between the experimental group and the control group.

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