Title

An analysis of the effectiveness of Quisqualis indica L. (Niyog-Niyogan) stem and leaf ethanolic extracts as antimicrobial agents against common pathogens Escherichia coli and Salmonella typhi

Date of Completion

2017

Document Type

Thesis

Degree Name

Clinical Pharmacology

Keywords

Medicinal Plants, Anti-Infective Agents, Escherichia coli, Salmonella typhi, Plant Extracts

Abstract

The plant locally referred to as niyog-niyogan has been known to posssess pharmacologic activity. The part of the plant with the most active phytochemicals are the flowers. There have been extended studies performed on the flowers of the plant thus the study focused on the leaves and stem to determine if pharmacologic activity may be comparable through an experimental determination of the Quisualis indica Linn. minimum inhibitory concentration and minimum bactericidal concentration. Herbal extraction, maceration with 95% ethanol and ROTAVAP extraction was performed on the sample for a standard agar dilution test. The inhibitory property exhibited by the Quisqualis leaf extract, was significant in inhibiting the growth of E. coli and S. typhi. Both extracts exhibited antimicrobial properties, but the leaf extracts possessed a greater antimicrobial property than the stems.

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