Title

Synergistic Antifungal Activity of Moringa oleifera Leaf Extracts and Fluconazole against Candida albicans

Date of Completion

5-24-2019

Document Type

Thesis

Degree Name

Bachelor of Science in Pharmacy

Keywords

antifungal, moringa oleifera, Candida alibicans, Plant Extracts

Abstract

The final concentration ranges of fluconazole and Moringa oleifera used were 0.0225μg/μL - 18.7μL and 75μg/μL - 1250μg/μL, respectively. The plate was incubated at 35°C for 20 hours. Optical density was measured on the absorbance at 492 nm using FLUOstar Omega Microplate Reader. The study concluded that there is a synergistic antifungal activity between Floconazole and Moringa oleifera leaf extracts at certain combined concentrations evaluated using checkerboard assay.

First Advisor

Michael John C. Rivera, RPh

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