Title

In vitro comparison of the effect of chlorhexidine mouth wash, normal saline solution, and apple cider vinegar on biofilm produced by streptococcus pyogenes, a causative agent of recurrent tonsillopharyngitis : an experimental study

Date of Completion

2017

Document Type

Thesis

Degree Name

Clinical Pharmacology

Keywords

Chlorhexidine, Mouthwashes, Saline Solution, Acetic Acid, Streptococcus pyogenes, Adenoids

Abstract

This study aimed to compare the effects of chlorhexidine mouth wash, normal saline solution, and apple cider vinegar on biofilm produced by streptococcus pyogenes. An in-vitro study involved the usage of different concentrations of chlorhexidine mouth wash, normal saline solution, and apple cider vinegar to eradicate the biofilm produced by streptoccoccus pyogenes. Antibiofilm property was determined by measuring the absorbances of the biofilm produced by streptococcus pyogenes after addition of the different test solutions. Based on the study, it was concluded that normal saline solution and apple cider vinegar do have antibiofilm properties against those produced by streptococcus pyogenes. 100% concentration for NSS and for 75% concentration for ACV showed the least amount of biofilm although there was no statistically significant difference compared to the other concentrations. The 100% concentration of the standard test group (0.12% chlorhexidine gluconate) was the most effective concentration versus the experimental test groups in reducing the amount of biofilm produced by streptococcus pyogenes.

Comments

This study aimed to compare the effects of chlorhexidine mouth wash, normal saline solution, and apple cider vinegar on biofilm produced by streptococcus pyogenes. An in-vitro study involved the usage of different concentrations of chlorhexidine mouth wash, normal saline solution, and apple cider vinegar to eradicate the biofilm produced by streptoccoccus pyogenes. Antibiofilm property was determined by measuring the absorbances of the biofilm produced by streptococcus pyogenes after addition of the different test solutions. Based on the study, it was concluded that normal saline solution and apple cider vinegar do have antibiofilm properties against those produced by streptococcus pyogenes. 100% concentration for NSS and for 75% concentration for ACV showed the least amount of biofilm although there was no statistically significant difference compared to the other concentrations. The 100% concentration of the standard test group (0.12% chlorhexidine gluconate) was the most effective concentration versus the experimental test groups in reducing the amount of biofilm produced by streptococcus pyogenes.

This document is currently not available here.

Share

COinS