Title

The efficacy of Arabian coffee (Coffea arabica) bean extract as an antifungal agent against opportunistic Fungi Candida albicans

Date of Completion

2017

Document Type

Thesis

Degree Name

Clinical Pharmacology

Keywords

Coffee, Antifungal Agents, Fungi

Abstract

This study aimed to determine the antifungal activity of Arabian coffee (Coffea arabica) bean extract as an antifungal agent against Candida Albicans. An analytical study that involved the treatment of Candida albicans with five different concentrations (1%, 5%, 10%, 20%) of Coffea arabica bean extract (intervention) and Fluconazole (standard treatment and positive control). Antifungal property was determined by comparing the zone of inhibition produced by the treatments. Anova (single factor) testing of the results showed that there was a statistically significant difference between Floconazole and the five different concentrations of Coffea arabica bean extract (1%, 5%, 10%, 15%, 20%). This was supported by the p-value = 0.00215 which was less than the 0.05 acceptance level. Based on this study, it was concluded that the extract of Coffea arabica was an ineffective antifungal agent against Candida albicans as it yielded negative inhibition on the fungal growth among the five tested concentrations.

This document is currently not available here.

Share

COinS