Determination and comparison of the effects of capsicum frutescents (siling labuyo, capsicum annuum var. longum (siling haba), and capsicum chinense (habanero) crude fruit extract on the degree of vascularization using chorioallantoic membrane (CAM) assay of a 7-day old duck embryo

Date of Completion

2017

Document Type

Thesis

Degree Name

Clinical Pharmacology

Keywords

Capsicum, Chick Embryo, Chorioallantoic Membrane

Abstract

This study was conducted to determine and compare the effect of Capsicum frutescens (siling Labuyo), Capsicum anuum var. Longum (siling Haba, and Capsicum chinense (Habanero) crude fruit extract on degree of vascularization using chorioallantoic membrane asasy of a 7-day old duch embryo. An experiemntal study that involved qualitative and quantitative methods to characterize the extract of different Capsicum species. The crude extracts were subjected to chorioallantoic membrane assay to determine the degree of vascularity of the different variants of Capsicum. Four contrations were prepred; 25%, 50%, 75%, 100%. Positive and negative control groups were 5% retinoic acid and normal saline solution, respectively. Statistical analysis of the quantitative data gathered was performed using ANOVA. This study had shown that there was no significant difference on the degree of vascularity among the speciies Capsicum fruttescens, Capsicum anuum var. Lngum, and Capsicum chinense against the negative control. In addition, results also demonstrated that there were no dose-dependent effects on the degree of vascularity for each species.

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