A comparative in vitro study of the antimicrobial properties of oil extracts of various citrus peels against S. aureus and S. pyogenes versus antimicrobial effects of mupirocin

Date of Completion


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Degree Name

Clinical Pharmacology


Anti-Infective Agents, Citrus, Mupirocin, Staphylococcus aureus, Streptococcus pyogenes


This study aimed to determine the antimicrobial properties of Citrus limon (Lemon), Citrofortunella microcarpa (Calamansi) and Citrus grandis (Pomelo) peel oil in inhibiting the growth of S. aureus and S. Pyogenes in Vitro. Diffusion disk method was utilized to compare zones of inhibition of the different citrus fruit peel oils from the standard drug (mupirocin) of use against S. aureus and S. pyogenes. The results revealed the presence of antimicrobial activity of Citrus grandis (Pomelo) against S. pyogenes. Citrus limon (Lemon) and Citrofortunella microcarpa (Calamansi) showed no antimicrobial activity against any of the microorganisms investigated in the study. On statistical analysis, the antimicrobial activity exhibited by Citrus grandis was not significant compared to the standard drug Mupirocin.

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