In vitro anthelmintic activity of Cassia Fistula Linn (golden shower tree) leaves aqueous extract in comparison to albendazole against Ascaris Suum (pork roundworm)

Elle Frances Aleksandra S. Bautista
Joanna Kierstine N. Billote
Mikylle Edraine C. Caringal
Aliyah Bianca M. Gianan
Andrew Jose C. Hipe


Anthelmintics are the drugs that are often used to treat worm infections like Helminthiasis, an infection caused by parasitic worms, contribute to the malnutrition, pneumonia, and overall decline of health by its host. Worms like, Ascaris suum, contaminates not only the humans but also animals where our daily food comes from. To help solve this crisis, Cassia fistula (golden shower tree) leaves aqueous extract will be used against Ascarissuum (pork roundworm) to determine its anthelmintic activity in comparison with Albendazole. Samples of plants will be collected, authenticated, air dried, filtered and free-dried through lyophilization. The worms will be collected and authenticated. The aqueous extract of Cassia fistula and Albendazole will be used against Ascarissuum. Worms soaked in different treatment and temperature will be observed simultaneously. Statistical analysis using Two-Way Analysis of Variance (ANOVA) will be used to determine any significant differences between the means of three or more independent groups. A single factor or one-way ANOVA will be used to determine whether the null hypothesis which states that the means of several populations are all equal.