Neurologic outcome of Filipino children diagnosed with central nervous system infection

Authors

Aida M. Salonga M.D, Institute of Child Health and Human Development, National Institutes of Health-University of the Philippines Manila
Peter Francis Raguindin M.D, Institute of Child Health and Human Development, National Institutes of Health-University of the Philippines Manila
Mishelle H. Imperial M.D, Child Neurosciences Center, Philippine Children’s Medical Center
Marilyn H. Ortiz M.D, Child Neurosciences Center, Philippine Children’s Medical Center
Martha L. Bolaños M.D, Department of Neurosciences, Philippine General Hospital, University of the Philippines Manila
Maria Lourdes M. Trajano M.D, Baguio General Hospital and Medical Center
Madeleine Grace M. Sosa M.D, De La Salle University Medical Center, De La Salle Health Sciences Institute
Bernadette Chua-Macrohon M.D, Zamboanga City Medical Center
Jo Janette R. de la Calzada M.D, Cebu Doctors University Hospital
Maria Lourdes E. Amarillo M.D, Department of Clinical Epidemiology, College of Medicine, University of the Philippines Manila, Philippines

Publication Date

2019

Document Type

Article

Publication Title

Neurology Asia

Abstract

Background: Neurologic infections are related to chronic and life-long neurologic impairment. We aim to describe the outcomes of Filipino children with neurologic infections upon, and within one year from discharge. This data will be useful in developing programs for the prevention and improvement of outcomes in children with neurologic infections.

Methods: This is a multicenter, cross-sectional, retrospective cohort study at six tertiary hospitals across the Philippines within four years (2007-2010). A standardized report form was used to collect clinical profile and outcome using inpatient and outpatient records. Neurologic outcome was classified and staged at 3-, 6-, 9- and 12-months postdischarge.

Results: A total of 480 patients were included in the analysis (mean age 4.7 ± 5.3 y), most were bacterial in etiology (275 cases, or 57.3%). Severity of illness on admission (Stage 3, p

Conclusion: Outcomes of neurologic infections in children are dynamic. Close monitoring of the neurodevelopmental status after treatment is recommended to institute early intervention and rehabilitation programs that can modify the long-term outcome for children.

First Page

235

Last Page

242

APA Citation

Salonga, A. M., Raguindin, P., Imperial, M. H., Ortiz, M. H., Bolaños, M. L., Trajano, M. M., Sosa, M. M., Chua-Macrohon, B., de la Calzada, J. R., & Amarillo, M. E. (2019). Neurologic outcome of Filipino children diagnosed with central nervous system infection. Faculty Research and Scholarly Works.
Retrieved from https://greenprints.dlshsi.edu.ph/faculty_scholarly_works/320