Title

Antiangiogenic properties of ethanolic extract of Iponoea batatas (sweet potatoes) peeling

Date of Completion

2017

Document Type

Thesis

Degree Name

Bachelor of Science in Medical Laboratory Science

Keywords

Iponoea batatas, Angiogenesis Inhibitors, Ethanol

Abstract

The ipomoea batatas peelings were extracted using the soxhlet apparatus, evaporated under reduced pressure of 50°C and freeze dried at De La Salle University-Manila to obtasin a solid material. Choroioallantoic membrane assay was used in this study. Different concentrations of treatments were administered to the fertilized chicken eggs to examine the anti-angiogenic property of the crude extracts. The results of the study showed a significant (p<0.05) inhibition of blood vessels in treated eggs, as compared to the negative control. With all the given concentration of Ipomoea batatas , 3.3 mg was found to be the optimal concentration that was capable of inhibiting the growth of blood vessels. Furthermore, it was observed that all of the treatment has no significant difference compared to the positive control in inhibiting the proliferation of blood vessels. The study concluded that the different concentrations of ethanolic extracts of Ipomoea batatas peelings exhibited anti-angiogenic activity.

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