Title

Hypoglycemic effects of gypsophila paniculata (Baby's Breath) root extract on Streptozocin-induced diabetes in Sprague Dawley rats

Date of Completion

2018

Document Type

Thesis

Degree Name

Bachelor of Science in Medical Laboratory Science

Keywords

Diabetes, Rats, Streptozocin

Abstract

The study used an experimental design. A total of 25 Sprague Dawley rats were used for this study. The rats were administered with Streptocozin to induce diabetes. The rats were divided into 5 groups of 5 rats each. Group 1 was treated with metformin, Group 3,4,5 was treated with different concentration of Baby's Breath extract, 100 mg/kg, 150 mg/kg and 200 mg/kg respectively. Group 1 served as the negative control group and was administered with only Normal Saline Solution. Fasting Blood Glucose was determined every three (3) days for six (6) days. Based on the results, the rats treated with 200 mg/kg of Baby's Breath extract possess a hypoglycemic effect. It was concluded that the Baby's breath extract posses a hypoglycemic effect by decreasing the blood glucose level of the rats.

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