Title

Correlation of low density lipoprotein and selected hematologic parameters in hyperlipidemic-induced rabbits

Date of Completion

2018

Document Type

Thesis

Degree Name

Bachelor of Science in Medical Laboratory Science

Keywords

Lipoproteins, Rabbits, Hematologic Tests

Abstract

The study was conducted in Angelo King Medical Center, De La Salle Medical and Health Science Institute, Dasmarinas, Cavite. The researchers examine the correlation of LDL-C to NLR, PLR and MPV in 18 hyperlipidemic-induced New Zealand rabbits divided positive and negative control groups to identify the potential relationship of the 2 different set of laboratory parameters. Statistical data were computed using t-test, one-way ANOVA, Pearson r correlation and post-hoc Bonferroni multiple comparisons test. It showed that NLR is the parameter that is linked to LDL-C, showing a strong-positive correlation after successfully inducing a high fat diet in animal subjects. While, PLR and MPV present weak to moderate correlation to LDL values. The study concluded that obtaining the NLR value from a complete blood count laboratory result may help pre-determine the amount of LDL-C present in the body.

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