Title

Antimicrobial property of Curcuma longa (Turmeric) against extended spectrum beta Lactamase-Escherichia coli and methicillin-resistant Staphyloccus aureus

Date of Completion

2017

Document Type

Thesis

Degree Name

Bachelor of Science in Medical Laboratory Science

Keywords

Turmeric, Escherichia coli, Methicillin-Resistant Staphylococcus aureus

Abstract

This study used an experimental and quantitative method. This study had ESBL E.coli and MRSA as its variables of interest that was tested upon an antimicrobial plant extract of Curcuma longa. This study investigated and compared three (3) groups which are the positive control, negative control and treatment group. The study concluded that the concentrations 100mg/mL, 150 mg/mL, 175 mg/mL and 225 mg/mL of turmeric have an antimicrobial effect on MRSA. The same concentrations and a pure turmeric extract of 1150 mg have no antimicrobial property against ESBL E. coli. The results of the study showed that minimum inhibitory concentration of turmeric extract is 1.56 mg/mL against MRSA. The optimum bactericidal concentration of turmeric extract against MRSA is 75 mg/mL, which shows a paradoxical effect against the bacteria.

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