Title

Efficacy of phenol-rich maple syrup in enhancing piperacillin-tazobactam against the clinical isolate of pseudomonas aeruginosa

Date of Completion

2017

Document Type

Thesis

Degree Name

Bachelor of Science in Medical Laboratory Science

Keywords

Pseudomonas aeruginosa, Maple, Piperacillin, Tazobactan

Abstract

Modified microdilution assay was used for the evaluation of the synergistic effect between piperacillin-Tazobactam and prenol-rich maple syrup inhibition of pseudomonas aeruginosa. The results of the study found out that the MIC of the piperacillin-tazobactam against the clinical isolate of P. aeruginosa is 0.13 mg/100 mL which is located on the 4th well of the microtiter plate. On the other hand, there is an inhibitory effect on piperacillin-tazobactam enhanced with penol-rich maple syrup shown on the A1 well of the 50%, 60% and 70% mixture of phenol-rich maple syrup. The study concluded that the piperacillin-tazobactam was able to inhibit pseudomonas aeruginosa and there is a synergistic mixture between piperacillin-tazobactam and phenol-rich maple syrup.

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